Lactate treatment regulates epigenome of mouse embryonic stem cells (mESCs)
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https://www.ncbi.nlm.nih.gov/sra/SRP351866
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资源简介：
We treated mESCs with 50mM lactate to examine its impact on mESC epigenome. Interestingly, we found that lactate supplementation stimulated H3K18 lactylation accumulation on a subset of genes, which in turn promoted transcriptional elongation. Our results indicate that lactate supplementation expands transcriptional network of mouse ESCs. Overall design: We treated mESCs with lactate, and produced libraries to identify changes of epigenome.
创建时间：
2022-02-28
