Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-N-[4-(4-chlorophenyl)sulfonylphenyl]-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide

Protein Data Bank Japan2026-02-18 更新2026-03-21 收录

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Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-N-[4-(4-chlorophenyl)sulfonylphenyl]-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide Descriptor: (2Z)-N-[4-(4-chlorobenzene-1-sulfonyl)phenyl]-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... Authors: Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. Deposit date: 2023-02-08 Release date: 2024-02-21 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of a human cyclic GMP-AMP synthase complex To be published

人类环状GMP-AMP合酶与(Z)-N-[4-(4-氯苯基)磺酰基苯基]-2-氰基-3-羟基-3-(5-甲基-1,2-恶唑-4-基)丙-2-烯酰胺的晶体结构描述符：(2Z)-N-[4-(4-氯苯-1-磺酰基)苯基]-2-氰基-3-羟基-3-(5-甲基-1,2-恶唑-4-基)丙-2-烯酰胺、腺苷5'-三磷酸（ADENOSINE-5'-TRIPHOSPHATE）、环状GMP-AMP合酶（Cyclic GMP-AMP synthase）等作者：Leibrock, L、Benz, J、Groebke-Zbinden, K、Rudolph, M.G. 沉积日期：2023-02-08 发布日期：2024-02-21 末次修改日期：2026-02-18 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.65 Å）引用文献：《人类环状GMP-AMP合酶复合物的晶体结构》，待发表

创建时间：

2023-02-08