PNNP Macrocycles: A New Class of Ligands for Asymmetric Catalysis|不对称催化数据集|化学合成数据集

We report the first examples of enantiomerically pure P2N2 macrocycles containing either a diimino (1a) or diamino donor set, as well as their ruthenium(II) dichloro complexes. Unexpectedly, the diimino derivative 2a is a more efficient catalyst in the transfer hydrogenation of acetophenone than its diamino analogue.

本报告首次揭示了含有二亚胺（1a）或二胺供体基团的P2N2手性大环化合物及其钌(II)二氯化物复合物。出人意料的是，二亚胺衍生物2a在苯乙酮转移加氢反应中的催化效率高于其二胺类似物。