Double Reduction of Cyclic Aromatic Sulfonamides: Synthesis of (+)-Mesembrine and (+)-Mesembranol
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https://figshare.com/articles/dataset/Double_Reduction_of_Cyclic_Aromatic_Sulfonamides_Synthesis_of_Mesembrine_and_Mesembranol/2426734
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资源简介:
The synthesis of
(+)-mesembrine (1) and (+)-mesembranol
(2) has been achieved from the monoterpene (S)-(−)-perillyl alcohol. Key transformations include a diastereo-
and regioselective Pd-mediated intramolecular Heck reaction, and a
double reduction of the resultant cyclic sulfonamide, to afford the cis-3a-aryloctahydroindole skeleton.
创建时间:
2016-02-19



