JUN binds MAPK6 gene
收藏reactome.org2025-01-16 收录
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MAPK6 expression is stimulated in response to cytokines through JUN-mediated transcriptional activation. Phosphorylated JUN binds to a canonical JUN-binding site in the MAPK6 gene as assessed by ChIP, and stimulates transcription in response to TNFalpha (Wang et al, 2014).
MAPK6 表达在细胞因子刺激下,通过 JUN 介导的转录激活作用而被激活。磷酸化的 JUN 与 MAPK6 基因中的经典 JUN 结合位点结合,如 ChIP 所评估,并在 TNFalpha 刺激下促进转录(Wang 等人,2014)。
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