Brg1 enables rapid growth of the early embryo by suppressing genes that regulate apoptosis and cell growth arrest

Global gene expression analysis revealed that genes up regulated in Rosa26CreERTM; Brg1floxed/floxed embryos (Rosa26CreERTM; Brg1floxed/floxed hereafter referred as Brg1d/d that is designated for deleted Brg1floxed/floxed alleles in embryos) negatively regulate cell cycle progression, and cell growth. RNA from Brg1floxed/floxed (wild type control) Day 8.5 embryos (three biological replications) and RNA from Brg1d/d (Brg1 CKO: conditional knockout) Day 8.5 embryos (three biological replications) were used for global gene expression analysis.