Association of C3 haplotype blocks with wet AMD.

OR: odds ratio; CI: confidence intervals.The association of haplotype CC in block 4 remained statistically significant after correction for multiple testing (permutation P = 0.011).*The P-values were calculated by the chi-square test on haplotype counts (1 degree of freedom).†The omnibus P-values were calculated by the PLINK software (4 degrees of freedom for block 1; 2 degrees of freedom for block 2, 4, and 5; 3 degrees of freedom for block 3).