DeBoeck2021 - Modular approach to modeling the cell cycle, simple cell cycle model
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https://www.omicsdi.org/dataset/biomodels/BIOMD0000001079
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Models the production and degradation of cyclin B that drives the early embryonic cell cycle.
Cyclin B is degraded by APC/C. The activity of APC/C is modeled not through biochemical interactions, but through a 'functional response curve'. This can be ultrasensitive (with the parameter alpha=0). in this case the system does not oscillate. Importantly the response can be made bistable and the form of the bistability can be easily prescribed. With a bistable response, the system oscillates.
The uploaded file corresponds to the model used for Figs.3H, I in the publication.
创建时间:
2024-09-02



