Summary statistics for the MAS meta-analysis for major depression (AHRR model)

This dataset contains the summary statistics from a large-scale meta-analysis of methylome-wide association studies (MWAS) for Major Depression (MD), conducted by the Psychiatric Genomics Consortium Major Depressive Disorder Working Group and published in Nature Mental Health. The analysis included data from 18 studies comprising 24,754 European-ancestry participants (5,443 MD cases) and an East Asian sample (243 cases, 1846 controls). The study identified fifteen CpG sites significantly associated with lifetime MD, and provided evidence for the involvement of DNA methylation and immune system in MD.