Details of the experimental conditions tested and summary of the antitumor effects achieved.

In all experiments except 1B and 1C, the pulses were delivered in 2 perpendicular orientations. The EP were delivered using a Cliniporator in all conditions except 1L, 2B and 2F for which a Jouan device was used (see Methods). Exp: experimental condition; n: number of pulses; t: individual pulse duration; U/d: voltage to distance ratio (approximate electric field strength); d: distance between the plate electrodes; f: repetition frequency; Tmax: theoretical maximum temperature; t43: theoretical equivalent thermal dose; CR: number of complete regressions/number of treated tumors, and percentage of CR.