five

Lung expression data from young and old mice at ZT0 and ZT12

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261207
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Circadian rhythms control the diurnal nature of many physiological, metabolic and immune processes. Circadian rhythms are tighly controlled by positive and negative transcriptional loops; This circuitry is altered during aging altering tissue daily function. We used microarrays to detail the global programme of gene expression underlying age-mediated alteration of the transcriptional progarm in lungs. Lungs from 2-month-old and 18-month-old male mice were harvested at ZT0 (light on) and ZT12 (light off). RNA were then extracted and hybridised on a Affymetrix microarrays.
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2025-03-28
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