PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
收藏官方服务：
资源简介：
PTIP promotes chromatin changes critical for immunoglobulin class switch recombination
应用场景：
创建时间：
2010-08-25
相关数据集
Immunoglobulin class-switch recombination downregulates Blimp1-driven IL-10 production in IgM+CD138hi cells
To determine characterize IL-10 producing CD138hi cells, we compared the global gene expression of primary B220+ B cells in spleen, freshly isolated Venus+ CD138hi cells in bone marrow and spleen of I
NIAID Data Ecosystem70
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient
NIAID Data Ecosystem40
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining. CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining
To generate antibodies with different effector functions, B cells undergo Immunoglobulin class switch recombination (CSR). The ligation step of CSR is usually mediated by the classical non-homologous
NIAID Data Ecosystem30
Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro
This is a comparative microarray analysis of 36-65 hybridomas switching at normal low frequencies in vitro vs. selected variants spontaneously switching at 100 fold higher frequencies in vitro. This
NIAID Data Ecosystem50
RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. MOLECULAR-CELL-D-17-01580, Ribeiro de Almeida at al.
Raw files for “RNA helicase DDX1 modulates G-quadruplex and R-loop formation to promote IgH Class Switch Recombination". MOLECULAR-CELL-D-17-01580, Ribeiro de Almeida at al.
NIAID Data Ecosystem40
