NIAID Mulit-Center AIDS Cohort Study (MACS). NIAID Mulit-Center AIDS Cohort Study (MACS)

The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles. A total of 6,972 men have been enrolled. From April 1984 through March 1985, 4954 men were enrolled; an additional 668 men were enrolled from April 1987 through September 1991. A third enrollment of 1,350 men took place between October 2001 and August 2003. Of the 6,972 enrolled men, approximately 3,564 (51%) are infected with HIV. MACS is intended to evaluate predictors and outcomes of HIV infection and treatment with greater depth and breadth than that ascertained in standard clinical care. Towards this end, MACS participants have answered detailed questionnaires, donated samples and undergone testing, some contributing more than 30 years' worth of data. The MACS interview includes: behavior (particularly those related... (for more see dbGaP study page.)