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Crystal Structure of Human p38alpha complexed with a pyridinone compound

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal Structure of Human p38alpha complexed with a pyridinone compound Descriptor: 1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 Authors: Shieh, H.-S, Williams, J.M, Stegeman, R.A, Kurumbail, R.G. Deposit date: 2009-06-03 Release date: 2009-09-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg.Med.Chem.Lett., 19, 2009
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2009-06-03
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