RNA-seq of spinal cord, brain, liver, and muscle from an SMA mouse model
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RNA-seq of spinal cord, brain, liver, and muscle from an SMA mouse model
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创建时间：
2016-08-25
相关数据集
Expression data from SMA fibroblasts treated with amiloride or EIPA. Expression data from SMA fibroblasts treated with amiloride or EIPA
Spinal muscular atrophy (SMA) is an autosomal recessive, pediatric-onset disorder caused by the loss of spinal motor neurons thereby leading to generalized muscle atrophy. SMA is caused by the loss of
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Expression data from female rat retroperinoneal fat tissue. Expression data from female rat retroperinoneal fat tissue
Obesity is a complex disease with many causes, including a possible role of environmental chemicals. Perfluorohexane sulfonate (PFHxS) is one of many per- and polyfluoroalkyl substances (PFASs) freque
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Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron‑2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a loss of function mutation of the surviva
Figshare2018-12-13 更新00
Establishment, Characterization, and Tissue Comparison of Canine Pancreatic and Endometrial Organoids, Alongside Patient Matched Organoids
Organoids are 3-dimensional (3D) stem cell-derived cultures that offer a variety of technical advantages compared to traditional 2-dimensional (2D) cell cultures. Although murine models have proved us
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R-Roscovitine improves motoneuron function in mouse models for Spinal Muscular Atrophy.
Neurotransmission defects and motoneuron degeneration are hallmarks of Spinal Muscular Atrophy, a monogenetic disease caused by the deficiency of the SMN protein. In the present study, we show that sy
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