Interstitial null-distance time-domain diffuse optical spectroscopy using a superconducting nanowire detector

We demonstrate a novel realization of Interstitial fiber, broadband, Time Domain Diffuse Optical Spectroscopy (TD-DOS) in Null Source-Detector separation (NSDS) approach without temporal gating, by using a Superconducting Nanowire single photon detector (SNSPD) for acquisition. As per the MEDPHOT protocol, we test experimentally, the absorption linearity of the system on tissue-equivalent liquid phantoms, and demonstrate the scattering-independent retrieval of the absorption spectrum of water using Intralipid phantoms in the wavelength range of 600-1100 nm.

This work has been published in the Journal of Biomedical Optics - https://doi.org/10.1117/1.JBO.28.12.121202. Here, we present the dataset containing the acquired data pertaining to the aforementioned publication, including a brief overview, the tools to read it and the analysis corresponding to the figures in the article.