Kidney Models - A success Story
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.omicsdi.org/dataset/biostudies-other/S-DIXA-003
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Two renal cell-lines (human and rat) were assayed for gene changes resulting from carcinogen exposure in order to develop models for detecting carcinogens. The novel RPTEC/TERT1 cell was found to maintain excellent characteristics of the proximal tubule including transport capabilities and maintenance of a primary cilium. It also showed normal chromosomes and nuclear stability. It was therefore chosen as the human renal cell model. The NRK-52E cell line was chosen as the rat model in order to incorporate interspecies comparison and in vitro - in vivo comparison.
创建时间：
2017-07-21
