Mechanomics RT-DC Set 02 - Carcinoma

Entry is a part of <b>Mechanomics</b> collection (10.6084/m9.figshare.c.5399826) that contains materials supporting findings presented in the following manuscript:<i>Urbanska, M., Ge, Y.</i> et al.,<br><b><i>De novo identification of universal cell mechanics gene signatures</i></b>BiorXiv: https://doi.org/10.1101/2021.04.26.441418<i>;</i><i> </i><i>first published:</i><i> </i>27th April 2021<i>, last updated:</i><i> </i>4th Nov 2024<br>eLife: https://doi.org/10.7554/eLife.87930<i>; first published:</i><i> </i>23rd March 2023<i>, last updated:</i><i> </i>27th Dec 2024<br>This dataset contains mechanical measurement of six carcinoma cell lines obtained from RIKEN institute:<br>• ECC4 (RCB0982) - intestine - small-cell carcinoma<br>• TGBC18TKB (RCB0982) - intestine - adenocarcinoma• WA-hT (RCB2279) - lung - small-cell carcinoma<br>• EBC-1 (RCB1965) - lung - squamous cell carcinoma*• A549 (RCB0098) - lung - adenocarcinoma<br>• ECC10 (RCB0983) - stomach - small-cell carcinoma<br>• MKN45 (RCB1001) - stomach - adenocarcinoma<br>• MKN1 (RCB1003) - stomach - adenocarcinoma.<br>*this dataset was removed from later versions of the manuscriptMeasurements were performed using real-time deformability cytometry (RT-DC).<b>_rtdc.zip</b> - contains data acquired during the measurments in '*.rtdc' format<br><b>_tsv.zip</b> - contains extended data in a '*.tsv' format<b>_glmm.zip</b> - contains result summaries of statistical analysis comparing Young's moduli of the different cell types using generalised linear mixed effects models