Crystal structure of a CDK inhibitor bound to CDK2
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Crystal structure of a CDK inhibitor bound to CDK2 Descriptor: 4-[(4-{[(2R,3R)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide, Cyclin-dependent kinase 2 Authors: Ayaz, P, Andres, D, Kwiatkowski, D.A, Kolbe, C, Lienau, P, Siemeister, G, Luecking, U, Stegmann, C.M. Deposit date: 2016-02-25 Release date: 2016-04-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9. Acs Chem.Biol., 11, 2016
创建时间：
2016-02-25
