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Formal Nucleophilic Substitution of Bromocyclopropanes with Azoles

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Figshare2016-02-21 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Formal_Nucleophilic_Substitution_of_Bromocyclopropanes_with_Azoles/2533645
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A highly diastereoselective protocol for the formal nucleophilic substitution of 2-bromocyclopropylcarboxamides with azoles is described. A wide range of azoles, including pyrroles, indoles, benzimidazoles, pyrazoles, and benzotriazoles, can be efficiently employed as pronucleophiles in this transformation, providing expeditious access to N-cyclopropyl heterocycles.
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2016-02-21
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