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Reprogramming of human primary somatic cells by OCT4 and chemical compounds

ChEBI2010-12-03 更新2026-07-21 收录

细胞重编程

化学诱导多能性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-25218 数据链接链接失效反馈

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资源简介：

Reprogramming of human primary somatic cells by OCT4 and chemical compounds

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创建时间：

2010-12-03

细胞重编程

R-loop调控

R-loop induces genome instability and regulates gene expression. However, regulatory mechanism of R-loop in stem cell biology remains unclear. Here, we mapped the profiling of R-loops during reprogram

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Employing totipotent cells to reconstruct embryogenesis. Employing totipotent cells to reconstruct embryogenesis

细胞重编程

胚胎发育模型

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem50

C2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate. Mus musculus

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Direct reprogramming of human fibroblasts towards beta-like cells

细胞重编程

β细胞分化

We reprogrammed human foreskin fibroblasts towards beta-like cells via adenovirus-mediated sequential introduction of five transcription factors (Ngn3, Pdx1, Mafa. pax4, Nkx2-2). At day 11 after initi

NIAID Data Ecosystem60

Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors. Mus musculus

细胞重编程

骨骼肌细胞

Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology doe

NIAID Data Ecosystem50

Reprogramming of human primary somatic cells by OCT4 and chemical compounds

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