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Structure of human PARP1 domains (Zn1, Zn3, WGR, HD) bound to a DNA double strand break.

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Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Structure of human PARP1 domains (Zn1, Zn3, WGR, HD) bound to a DNA double strand break. Descriptor: DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*CP*GP*CP*AP*T)-3'), Poly [ADP-ribose] polymerase 1, ZINC ION Authors: Rouleau-Turcotte, E, Pascal, J.M. Deposit date: 2021-09-17 Release date: 2022-06-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Captured snapshots of PARP1 in the active state reveal the mechanics of PARP1 allostery. Mol.Cell, 82, 2022
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2021-09-17
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