Identification of Tryptophan Metabolism-Related Biomarkers in Kawasaki Disease

Transcriptomic data were obtained from the Gene Expression Omnibus (GEO; https://www.ncbi.nlm.nih.gov/geo/). The training set, GSE68004 (platform GPL10558), consists of peripheral blood samples from 76 patients with KD and 37 healthy controls. To validate these findings, the GSE73461 dataset (also on GPL10558) was used, which consists of samples from 78 patients with KD and 55 controls. In addition, a curated list of 40 TMRGs was retrieved from the Molecular Signatures Database (https://www.gsea-msigdb.org/gsea/msigdb/) for subsequent analyses.