Human PFKFB3 in complex with an indole inhibitor 3
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ajx
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Human PFKFB3 in complex with an indole inhibitor 3 Descriptor: (2S)-N-[4-[3-cyano-1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]indol-5-yl]oxyphenyl]pyrrolidine-2-carboxamide, 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, ... Authors: Boyd, S, Brookfield, J.L, Critchlow, S.E, Cumming, I.A, Curtis, N.J, Debreczeni, J.E, Degorce, S.L, Donald, C, Evans, N.J, Groombridge, S, Hopcroft, P, Jones, N.P, Kettle, J.G, Lamont, S, Lewis, H.J, MacFaull, P, McLoughlin, S.B, Rigoreau, L.J.M, Smith, J.M, St-Gallay, S, Stock, J.K, Wheatley, E.R, Winter, J, Wingfield, J. Deposit date: 2015-02-27 Release date: 2015-04-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase Pfkfb3. J.Med.Chem., 58, 2015
创建时间：
2015-02-27
