Identification of LGR6-associated genes in NSCLC
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP408372
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资源简介:
mRNA seq analysis comparing the expression profiles of siRNA-mediated LGR6-silenced and LGR6-retained NSCLC cell lines harboring CTNNB1 exon 3 mutations identified several LGR6-related genes that have been associated with cancer development and stemness properties. Overall design: HCC15 and A427 NSCLC cell lines were used in the current study. Gene expression was examined in siRNA-mediated LGR6-silenced NSCLC cells and LGR6-retained (control siRNA-treated) NSCLC cells. Cells were transfected with siRNAs targeting LGR6 and were collected at 48 h post-transfection, followed by total RNA extraction from the cells.
创建时间:
2024-01-30



