Transcriptome analysis of murine spinal cord in space.. Mus musculus

Our study aims to comprehensively understand the epigenetic effects induced by the space environment on mammals. To achieve this aim, we analyze the male mice housed under environments as the artificial gravity and the microgravity (space environment) in Japanese Experiment Module (JEM) of the International Space Station (ISS) on orbit for 35 days. After recovered these mice on the ground, transcriptome analysis by next-generation sequencing technology is performed about each organ to examine alteration of gene expression in the space. Specific modification of histone will be also analyzed.