ABCB1 and OPRM1 single-nucleotide polymorphisms collectively modulate chronic shoulder pain and dysfunction in South African breast cancer survivors: supplementary data

Name: ABCB1 and OPRM1 single-nucleotide polymorphisms collectively modulate chronic shoulder pain and dysfunction in South African breast cancer survivors: supplementary data
Creator: Taylor & Francis
Published: 2024-05-18 02:51:39
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DataCite Commons2024-05-18 更新2025-04-15 收录

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https://tandf.figshare.com/articles/dataset/ABCB1_and_OPRM1_single-nucleotide_polymorphisms_collectively_modulate_chronic_shoulder_pain_and_dysfunction_in_South_African_breast_cancer_survivors_supplementary_data/20106041

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Background: Chronic shoulder pain/disability is a well-recognized side effect of treatment for breast cancer, with ∼40% of patients experiencing this, despite receiving pain management. To manage acute and chronic pain, several opioids are commonly prescribed. Pharmacogenomics have implicated genes within the opioid signaling pathway, including ABCB1 and OPRM1, to contribute to an individual’s variable response to opioids. Aim: To evaluate ABCB1 (rs1045642 G>A, rs1128503 G>A) and OPRM1 (rs1799971 A>G, rs540825 T>A) single-nucleotide polymorphisms (SNPs) in chronic shoulder pain/disability in BCS.

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Taylor & Francis

创建时间：

2022-06-21