DNA-seq (low-coverage WGS) for validation of CRISPR-Cas9-edited mESCs

ChEBI2024-09-04 更新2026-07-12 收录

CRISPR-Cas9基因编辑

小鼠胚胎干细胞基因组测序

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12867 数据链接链接失效反馈

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资源简介：

DNA-seq (low-coverage WGS) for validation of CRISPR-Cas9-edited mESCs

创建时间：

2024-09-04

Crystal structure of xCas9 P411T

蛋白质晶体结构解析

CRISPR-Cas9基因编辑

Crystal structure of xCas9 P411T Descriptor: CRISPR-associated endonuclease Cas9/Csn1 Authors: Bao, R, Liu, H.Y, Luo, Y.Z, Song, Y.J. Deposit date: 2021-09-29 Release date: 2022-04-06 Last modified: 2

Protein Data Bank Japan2023-11-29 更新50

RNA_expression_profile_of_Cas9_cancer_cells. RNA_expression_profile_of_Cas9_cancer_cells

癌细胞转录组

CRISPR-Cas9基因编辑

RNA was collected from cancer cell lines(EVSA-T, LnCAP, HCC-70 and ZR-75-1) expressing Cas9 for RNA-seq. RNA expression profiles will be compared to the parental cell lines from which the Cas9 clones

NIAID Data Ecosystem40

CRISPR-Cas9 RBM10 synthetic lethality screen. CRISPR-Cas9 RBM10 synthetic lethality screen

CRISPR-Cas9基因编辑

合成致死筛选

Genome-wide CRISPR-Cas9 knockout screen using TKOv1 sgRNA library was performed in isogenic RBM10-proficient and RBM10-deficient HCC827 cells.

NIAID Data Ecosystem20

CRISPR Screening Reveals a Novel Role for FOXH1 in Regulating Pluripotency of Porcine Embryonic Stem Cells

胚胎干细胞多能性调控

CRISPR-Cas9基因编辑

pESCs hold significant potential for applications in regenerative medicine and stem cell-based breeding programs. However, the regulatory mechanisms governing pluripotency in pESCs, including aspects

NIAID Data Ecosystem40

Human HFF cells large rearrangements detection after CRISPR-Cas9 nuclease (Fig. 3b)

CRISPR-Cas9基因编辑

遗传效应分析

SORSC1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q. One condition

NIAID Data Ecosystem30

DNA-seq (low-coverage WGS) for validation of CRISPR-Cas9-edited mESCs

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