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Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor Descriptor: (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ACETATE ION, GLYCEROL, ... Authors: Diao, J, Chen, P, Yao, Y, Prasad, B.V.V, Song, Y. Deposit date: 2011-07-06 Release date: 2011-10-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies. J.Am.Chem.Soc., 133, 2011
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2011-07-06
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