The uterine microbiome in endometrial cancer patients

In the presented study, the endocervical canal microbiomes of women with endometrial cancer (EC) or endometrial myoma (EM) were examined. Microbial communities in endometrial samples significantly differed between the two groups, with EC samples exhibiting higher microbial diversity. Pathogenic taxa such as Streptococcus, Anaerococcus, Prevotella, Gardnerella, Peptoniphilus, and Porphyromonas were enriched in EC samples. Interestingly, the genus Anaerococcus was found to be a differentiating taxon between microbiomes isolated from women with EC and those with benign lesions (EM).