Data from: Peptide OA-VI12 restrains excessive melanogenesis in vitro and in vivo via the miR-122-5p/MITF/TYR axis

Ear tissues of C57B/6 mice from the Control, Model, and OA-VI12 groups were removed, and total RNA (three cases in each group) was extracted and sent to Beijing Guoke Biotechnology Co., Ltd. (China) for miRNA sequencing. Differential expression analysis of two conditions/groups was performed using the DESeq R package. The resulting p-values were adjusted using Benjamini-Hochberg correction to control the false discovery rate (FDR). Genes with an adjusted p-value < 0.01 and absolute value of log2(fold-change) > 1 were considered differentially expressed. The ClusterProfiler R package was used to identify significantly enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways (http://www.genome.jp/kegg/) compared to the entire genome background.

 All.DEG_final_anno.xls： All differential miRNA expression + differential information + target gene annotation results of each database

miRNA_expression.xls: expression amount files of all miRNAs

 miRNA_counts.xls: Count files of all miRNAs

 All.DEG_final_target.xls: Predicted target files for all miRNAs