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Replication of heritability of Rheumatoid Arthritis in ImmunoChip data.

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https://figshare.com/articles/dataset/_Replication_of_heritability_of_Rheumatoid_Arthritis_in_ImmunoChip_data_/887126
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Components of heritability for Rheumatoid Arthritis are shown at (A) previously known GWAS loci and (B) non-RA autoimmune loci in 4,395 WTCCC samples and 23,092 ImmunoChip samples. Autoimmune loci specifically exclude known RA regions, yielding equal to zero. Increase shown for over and local expectation from fraction of genome covered, highly significant for ImmunoChip samples in both panels. The well-studied MHC region was excluded entirely.
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2013-12-26
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