Synthesis, Anti-Diabetic and Renoprotective Activity of Some New Benzazole, Thiazolidin-4-one and Azetidin-2-one Derivatives
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https://scielo.figshare.com/articles/Synthesis_Anti-Diabetic_and_Renoprotective_Activity_of_Some_New_Benzazole_Thiazolidin-4-one_and_Azetidin-2-one_Derivatives/5667520
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资源简介：
A new series of benzazole, thiazolidinone and azetidin-2-one derivatives incorporating to pyrazole moiety were synthesized by condensation of 1,3-diphenyl-1H-pyrazol-4-carboxaldehyde with different nucleophiles. The structures of the newly synthesized compounds were confirmed by analytical and spectral methods. Some of these compounds were evaluated for their anti-hyperglycemic and renoprotective activities. Three compounds showed remarkable anti-diabetic potency, whereas other five compounds showed significant renoprotective activity.
提供机构：
SciELO journals
创建时间：
2017-12-05
