3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone

Protein Data Bank Japan2023-12-13 更新2026-03-21 收录

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3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as Inhibitors of the Hsp90 Molecular Chaperone Descriptor: HEAT SHOCK PROTEIN HSP90-ALPHA, N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE Authors: Brough, P.A, Barril, X, Beswick, M, Dymock, B.W, Drysdale, M.J, Wright, L, Grant, K, Massey, A, Surgenor, A, Workman, P. Deposit date: 2005-08-02 Release date: 2005-10-12 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: 3-(5-Chloro-2,4-Dihydroxyphenyl)-Pyrazole-4-Carboxamides as Inhibitors of the Hsp90 Molecular Chaperone. Bioorg.Med.Chem.Lett., 15, 2005

3-(5-氯-2,4-二羟基苯基)-吡唑-4-甲酰胺类作为热休克蛋白90（Hsp90）分子伴侣抑制剂描述项：热休克蛋白HSP90-α，N-(4-乙酰基苯基)-5-(5-氯-2,4-二羟基苯基)-1H-吡唑-4-甲酰胺作者：Brough, P.A、Barril, X、Beswick, M、Dymock, B.W、Drysdale, M.J、Wright, L、Grant, K、Massey, A、Surgenor, A、Workman, P 提交日期：2005年8月2日发布日期：2005年10月12日最后修改日期：2023年12月13日检测方法：X射线衍射（1.9埃）引用：3-(5-氯-2,4-二羟基苯基)-吡唑-4-甲酰胺类作为Hsp90分子伴侣抑制剂。Bioorg.Med.Chem.Lett., 15, 2005

创建时间：

2005-08-02