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Rhodium(III)-Catalyzed Synthesis of Spiropiperidine Derivatives via C–H Activation

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NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Rhodium_III_-Catalyzed_Synthesis_of_Spiropiperidine_Derivatives_via_C_H_Activation/5864079
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资源简介:
Spiropiperidine derivatives, an important class of bioactive molecules, were synthesized under mild conditions by rhodium­(III)-catalyzed intramolecular ArC–H activation. This reaction provides a novel route to highly substituted tricyclic spiropiperidines in good to excellent yields. Under acidic conditions the resulting enamines reacted with pendant amides to afford spiropiperidines derivatives possessing an original tetracyclic structure.
创建时间:
2018-02-07
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