Rhodium(III)-Catalyzed Synthesis of Spiropiperidine Derivatives via C–H Activation
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https://figshare.com/articles/dataset/Rhodium_III_-Catalyzed_Synthesis_of_Spiropiperidine_Derivatives_via_C_H_Activation/5864079
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资源简介:
Spiropiperidine
derivatives, an important class of bioactive molecules,
were synthesized under mild conditions by rhodium(III)-catalyzed intramolecular
ArC–H activation. This reaction provides a novel route to highly
substituted tricyclic spiropiperidines in good to excellent yields.
Under acidic conditions the resulting enamines reacted with pendant
amides to afford spiropiperidines derivatives possessing an original
tetracyclic structure.
创建时间:
2018-02-07



