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Crystal structure of human STING (G230A, H232R, R293Q) in complex with Compound 18

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Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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Crystal structure of human STING (G230A, H232R, R293Q) in complex with Compound 18 Descriptor: CALCIUM ION, Stimulator of interferon genes protein, [(3S,4S)-2-(4-tert-butyl-3-chlorophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1-oxo-1,2,3,4-tetrahydroisoquinolin-4-yl]acetic acid Authors: Lesburg, C.A, Siu, T, Ho, T. Deposit date: 2018-10-30 Release date: 2018-12-19 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING. ACS Med Chem Lett, 10, 2019
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2018-10-30
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