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SARS-CoV-2 macrodomain Nsp3b bound to the remdesivir nucleoside GS-441524

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Protein Data Bank Japan2024-01-31 更新2026-04-04 收录
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https://pdbj.org/mine/summary/7qg7
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SARS-CoV-2 macrodomain Nsp3b bound to the remdesivir nucleoside GS-441524 Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, 1,2-ETHANEDIOL, Papain-like protease nsp3 Authors: Wollenhaupt, J, Linhard, V, Sreeramulu, S, Weiss, M.S, Schwalbe, H. Deposit date: 2021-12-07 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity. J.Mol.Biol., 434, 2022
创建时间:
2021-12-07
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