Covalent GTP-competitive inhibitors of KRAS G12C: Guanosine bisphosphonate Analogs
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Covalent GTP-competitive inhibitors of KRAS G12C: Guanosine bisphosphonate Analogs Descriptor: 5'-O-[(R)-[({2-[(chloroacetyl)amino]ethyl}sulfamoyl)methyl](hydroxy)phosphoryl]guanosine, GTPase KRas Authors: Xiong, Y, Lu, J, Hunter, J, Li, L, Scott, D, Manandhar, A, Gondi, S, Westover, K.D, Gray, N.S. Deposit date: 2016-07-21 Release date: 2017-04-12 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Covalent Guanosine Mimetic Inhibitors of G12C KRAS. ACS Med Chem Lett, 8, 2017
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2016-07-21



