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PLA2G4E Orchestrates optimal Synapse Development and Neuronal Maturation [KO_Pla2g4e]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE259323
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Constitutive Pla2g4e knockout mice exhibited significant behavioral alterations, particularly in memory function, different brain lipid composition, and decreased levels of cortical synaptic plasticity markers compared to wild-type counterparts.We performed gene expression profiling analysis animals lacking PLA2G4E to study the function of this enzyme in memory function. Comparative gene expression profiling analysis of RNA-seq data obtained from prefrontal cortex of wild type and PLA2G4E knock out mice.
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2025-07-29
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