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Pseudomonas-derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate

ChEBI2014-12-25 更新2026-07-21 收录

皮肤炎症机制

角质形成细胞信号传导

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53670 数据链接链接失效反馈

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资源简介：

Pseudomonas-derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate

应用场景：

创建时间：

2014-12-25

皮肤炎症机制

表皮分化调控

Cellular FLICE-inhibitory protein (cFLIP) prevents the development of dermatitis by blocking TNFα-dependent apoptosis of keratinocytes. However, it is unclear whether TNFα-independent signal might als

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Production of Superoxide Anions by Keratinocytes Initiates P. acnes -Induced Inflammation of the Skin

皮肤炎症机制

角质形成细胞免疫应答

Acne vulgaris is a chronic inflammatory disorder of the sebaceous follicles. Propionibacterium acnes (P. acnes), a gram-positive anareobic bacterium, plays a critical role in the development of these

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TIMP3, a CLOCK-controlled gene, determines cell susceptibility to UV-induced expression of inflammatory factors in human keratinocytes.

皮肤炎症机制

生物钟基因调控

To search for CLOCK-controlled genes in human keratinocytes, we introduced siRNAs against CLOCK and harvested the cells at two time points, ZT 32 and 44. We speculated that those genes that were downr

NIAID Data Ecosystem30

Analysis of expression changes between IL-33 Knock out and WT mice in skin chronic inflammation. Analysis of expression changes between IL-33 Knock out and WT mice in skin chronic inflammation

皮肤炎症机制

差异基因表达分析

To find differential expression gene between IL-33KO and WT mice, we collected skin epithelial RNA sample after all of mice were treated with DNFB for 22 days. (allergen treat) After RNA-seq analysis,

NIAID Data Ecosystem70

Comparing transcriptional profiles of skin biopsies from healthy controls and subjects with chronic pruritus of unknown origin and atopic dermatitis

皮肤转录组学

皮肤炎症机制

Type 2 inflammation contributes to the pathology of pruritic skin diseases such as atopic dermatitis (AD). Chronic pruritus of unknown origin (CPUO) is a skin condition of unknown etiology that typica

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Pseudomonas-derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate

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