Next Generation Sequencing Facilitates Quantitative Analysis of Human Normal Tissues and Epileptic Tissues

Epilepsy is a neurological disease that causes serious implications on the quality of life of an individual. Through this study, we aimed to identify regulatory noncoding RNAs and mRNAs involved in Epilepsy. A RNA-seq analysis was conducted to determine epilepsy-related noncoding RNAs and mRNAs. In summary, the newly identified circRNAs in networks and signaling pathways found in this study would provide hints for the development of novel prognostic, diagnostic, and therapeutic strategies for Epilepsy. Overall design: Brain tissue mRNA, circRNA and lncRNA profiles of normal people and patients with epilepsy.