Crystal structure of DYRK1B in complex with AZ191

Crystal structure of DYRK1B in complex with AZ191 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1B, MANGANESE (II) ION, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine Authors: Grygier, P, Pustelny, K, Dubin, G, Czarna, A. Deposit date: 2022-12-23 Release date: 2024-01-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural perspective on the design of selective DYRK1B inhibitors To Be Published与AZ191结合的双特异性酪氨酸磷酸化调节激酶1B（DYRK1B）的晶体结构 描述：双特异性酪氨酸磷酸化调节激酶1B、二价锰离子、N-[2-甲氧基-4-(4-甲基哌嗪-1-基)苯基]-4-(1-甲基吡咯并[2,3-c]吡啶-3-基)嘧啶-2-胺 作者：Grygier P、Pustelny K、Dubin G、Czarna A 入库日期：2022-12-23 发布日期：2024-01-17 最后修改日期：2024-10-16 实验方法：X射线衍射（分辨率1.91埃） 引用：《选择性DYRK1B抑制剂设计的结构视角》，待发表