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Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target

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Surface Plasmon Resonance (SPR) is rarely used as a primary High-throughput Screening (HTS) tool in fragment-based approaches. With SPR instruments becoming increasingly high-throughput it is now poss

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CryoEM structure of DDB1-VprBP complex in ARM-up conformation Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1 Authors: Wang, D, Xu, J, Liu, Q, Xiang, Y. Deposit date: 2021

Protein Data Bank Japan2024-11-13 更新00

Crystal structure of Endothiapepsin in complex with fragment EOS102900 from ECBL-96

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