Cerebrovascular alterations in a mouse model of late-onset Alzheimer's disease

This collection of datasets is from three cohorts of mice. Mice in cohort
#1 had resting-state cerebral blood flow (CBF) measured with laser speckle
imaging (LSI) across different age groups (12, 18, and 22 – 27 m.o.) in
WT, hAβ-KI, and 3xTg-AD mice. Mice in cohort #2 utilized WT and hAβ-KI
mice at 23 – 25 m.o. and had bulk RNA-sequencing performed to examine
transcriptomics. Mice in cohort #3 utilized WT and hAβ-KI mice at 24 m.o.
to examine cerebrovascular structure and neurovascular coupling (NVC).
Datasets from cohorts #1 and #3 include the output data (e.g.,
resting-state CBF), mouse genotype, age group, and sex. Datasets from
cohort #2 include results from differential gene expression analysis
between genotypes and gene set enrichment analysis (GSEA) as .tsv files.