The effect of gene perturbation on the histone mark H3K27ac was evaluated in human Cas9 expressing MDA-MB231 cancers Human pancreatic cancer cell lines were cultured in DMEM supplemented with 10% feta

NIAID Data Ecosystem30

Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC) [MeRIP-seq]

癌症表观遗传学

RNA甲基化修饰

RNA N6-methyladenosine (m6A) plays diverse roles in RNA metabolism and its deregulation contributes to tumor initiation and progression. Clear cell renal cell carcinoma (ccRCC) is characterized by nea

NIAID Data Ecosystem00

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

MOESM4 of Uncoordinated expression of DNA methylation-related enzymes in human cancer

甲基化调控基因

癌症表观遗传学

Additional file 4: Table S2. Correlations among DNA methylation-related enzymes in 26 human tissues. The RNA-Seq gene expression data of 7 DNA methylation-related enzymes were obtained from the GTEx d

Figshare2023-06-01 更新20

Methyl-array of breast cancer cell lines with different metastatic potential

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