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Analysis of Polycomb Repressive Complex 1 subunits across cell cycle in pluripotent cells

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP386038
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We report ChIP-seq of PRC1 proteins and 4sU-seq, mRNA-seq, Capture-C and 4C-seq data using mouse embryonic stem cells sorted in different phases of the cell cycle. Overall design: ChIP-seq samples for Ring1b, Rybp, H2AK119ub1 and Cbx7 obtained from cell-cycle sorted FUCCI-mESCs (G1, S, G2 fractions). 4sU-seq data in cell cycle-sorted FUCCI-Ring1bfl/fl and FUCCI-Ring1b-/- mESCs. mRNA-seq data from cell cycle-sorted AID::Ring1b;FUCCI mESCs plated in differentiation media with IAA or without IAA during 6h. Capture-C data from G1 and G2 cell cycle-sorted FUCCI-Ring1bfl/fl and FUCCI-Ring1b-/- mESCs. 4C-seq data from G1 and G2 cell cycle-sorted FUCCI-Ring1bfl/fl and FUCCI-Ring1b-/- mESCs.
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2023-01-18
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