Crystal structure of p110beta in complex with icSH2 of p85beta and the drug GDC-0941
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Crystal structure of p110beta in complex with icSH2 of p85beta and the drug GDC-0941 Descriptor: 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM Authors: Zhang, X, Vadas, O, Perisic, O, Williams, R.L. Deposit date: 2010-12-20 Release date: 2011-03-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of Lipid Kinase P110Beta-P85Beta Elucidates an Unusual Sh2-Domain-Mediated Inhibitory Mechanism. Mol.Cell, 41, 2011
创建时间：
2010-12-20
