Burden of disease attributable to low physical activity in Zhejiang Province from 1990 to 2021

Objective To analyze the trend of disease burden attributable to low physical activity in Zhejiang province from 1990 to 2021.Methods Based on the data from the Global Burden of Disease Study 2021, the indicators such as years of life lost due to early death (YLL), years of life lost due to disability (YLD), years of life adjusted for disability (DALY) were used to describe the characters and changes of disease burden attributable to low physical activity stratified by different sex and age groups from 1990 to 2021.Results Firstly, from 1990 to 2021, the YLD rate, YLL rate, DALY rate attributed to low physical activity in Zhejiang province all showed an overall upward trend (with AAPC values of 3.43%, 2.27%, 2.52%, all P<0.05). The annual average growth rates of age-standardized YLD rate, DALY rate in Zhejiang province were higher than the national and global levels, while the annual average decline rates of age-standardized YLL rate in Zhejiang province were lower than the national and global levels in recent years. Secondly, the disease burden attributable to low physical activity in Zhejiang province shows differences by gender and age. The YLD rate, YLL rate, DALY rate attributed to low physical activity in Zhejiang province in 2021 were 31.56, 85.67 and 117.23 per 100 000, respectively. The YLD rate (38.50 vs 25.23 per 100 000), YLL rate (98.49 vs 73.94 per 100 000), DALY rate (136.99 vs 99.17 per 100 000) were all higher in females than those in males. The highest YLD rate (166.14 per 100 000), YLL rate (749.10 per 100 000), DALY rate (915.24 per 100 000) were observed in age group of 70 years and above, while the lowest YLD rate (10.29 per 100 000), YLL rate (7.62 per 100 000), DALY rate (17.92 per 100 000) were in 15-49 age group. However, the annual average growth rates of YLD rate, DALY rate in 15-49 age group (with AAPC values of 3.10% vs 1.22% and 1.35%, 1.75% vs -0.66% and 0.93%) were higher than those in the age group of 50-69 years,70 years and above, and the annual average growth rates were higher in males (with AAPC values of 3.71% vs 3.27%, 2.63% vs 2.03%, 2.84% vs 2.30%）than those in females. Thirdly, the main diseases related to low physical activity in Zhejiang province were stroke, diabetes, colorectal cancer, ischemic heart disease and chronic kidney disease, with increased DALY rates for all these conditions from 1990 to 2021.Conclusion From 1990 to 2021, the disease burden attributed to low physical activity in Zhejiang province showed an overall upward trend, with an growth rates in recent years which have remained higher than the national and global levels. Continued promotion of National Fitness Program is warranted, with a focus on intervention and guidance for young, middle-aged and old people, to effectively reduce burden disease attributable to low physical activity.