We induced liver tumors by transforming liver progenitor cells (LPC) with retroviruses expressing oncogenic Ras coupled to tetracycline transactivator together with an inducible shRNA targeting p53.
Micro-RNAs (miRNAs) are small non-coding RNAs that regulate gene expression, mainly at mRNA post-transcriptional level. Functional maturation of most miRNAs requires processing of the primary transcri
Tumorigenic potential of tumor sphere cells is greater than monolayer cancer cells. Monolayer and tumor sphere cells from A549 were injected s.c. into athymic nude mice at concentrations of 1×104 cell
These libraries represent instances of Swarm rat chondrosarcoma tumors taken from different transplantation experiments. This series also contains one non-cancerous cartilage library made from rat nor
