The methylome and transcriptome of murine foetal skin and scarless wound healing
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2017-04-01
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The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]. The RNA N6-methyladenosine regulates chromatin remodeling and transcription [seq_mettl3ChIP]
The N6-methyladenosine (m6A) has been shown to regulate stability and translation of messenger RNA (mRNA) in various biological processes. Here, we show that the knockout of the m6A writer Mettl3 or a
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Mass spectrometry on tRNAs from Tet1/2/3 tKO mESCs rescued with TET2 WT or catalytic mutant (HxD) and control (GFP)
Mass spectrometry analysis on tRNAs gel purified from Tet1/2/3 triple KO mouse embryonic stem cells after transient transfection of TET2 catalytic fragment wild type (WT), catalytic mutant (HxD), or a
Figshare2020-10-23 更新40
Single-base resolution methylome of 5-Methylcytosine in human and mouse transcriptome. Single-base resolution methylome of 5-Methylcytosine in human and mouse transcriptome
mRNAs of siCTRL, siNSUN2 and ALYREF-RIP HeLa cells, and multiple mouse tissues were purified using oligo (dT)-conjugated magnetic beads followed by RiboMinus treatement. mRNAs were fragmented to ~200
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Transcriptome Mapping of Internal N7-methylguanosine Methylome in Mammalian mRNA
N7-methylguanosine (m7G) is a positively charged, essential modification at the 5′ cap of eukaryotic mRNA, regulating mRNA export, translation, and splicing. m7G also occurs internally within tRNA and
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m6A mRNA modification is a rheostat to maintain colonic epithelial cell homeostasis [bulkRNA-seq]. m6A mRNA modification is a rheostat to maintain colonic epithelial cell homeostasis [bulkRNA-seq]
The function of m6A modification in colonic epithelial cells has been validated in our study that depletion of METTL14 in colonic epithelial cells triggers cell death. To further explore the biologica
NIAID Data Ecosystem40



